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NSU TRED

Translational Research and Economic Development (TRED) supports NSU’s innovative faculty within its colleges, centers and institutes in the development of their ideas, discoveries and technologies. Led by senior vice president H. Thomas Temple, M.D., TRED is the focal point for building the connections, resources and entrepreneurial energy for the commercialization of NSU’s research activities.

NSU is actively establishing partnerships with companies, investors and entrepreneurs interested in utilizing NSU’s vast wet and dry lab space and state-of-the-art Center for Collaborative Research (CCR) to conduct research and develop technologies that will benefit the global community.

TRED is home to a robust research infrastructure. This includes the Office of Research and Technology Transfer which is the overarching organization for the Office of Sponsored Programs, Office of Clinical Research, Office of Technology Transfer, and the Grant Writing Laboratory.

In the News

NSU Translational Research and Economic Development Genomics Core Facility to Host NanoString Technologies Seminar, Oct. 10

NSU’s Translational Research and Economic Development Genomics Core Facility will host the Introduction to NanoString Technologies seminar in the Buehler Institute of the Center for Collaborative Research on Tuesday, October 10 from 11:00 A.M. – 12:30 P.M. NanoString’s products utilize a novel digital molecular barcoding technology that is based on direct multiplexed measurement of gene expression without amplification and offers high levels of precision and sensitivity (< 1 copy per cell). The technology uses color-coded molecular barcoding and single molecule imaging to detect and count hundreds of unique transcripts in a single reaction using NanoString’s nCounter Analysis System. The Genomics Core Facility offers NanoString services using custom and pre-made panels to study defined gene sets for profiling specific expression signatures as well as microarray and next-generation sequencing validation. Contact NSUGenomics@nova.edu to discuss your research project or to request a quote. This is a free event. However, registration is required and seating is limited. Please visit the Genomics Core Facility website to RSVP.

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Halmos Faculty Studies Coral Reefs in Galapagos Islands

In April, Halmos faculty member Bernhard Riegl, Ph.D., traveled to the Galapagos Islands to work with a group of scientists from the Charles Darwin Foundation Scientists (CDF), Ecuador International Conservation (IC-Ecuador), ETPS Regional Program (Eastern Pacific Landscape), Nazca Institute of Marine Research and Nova Southeastern University to study three areas in the Galapagos Archipelago: i) the amount of seaweed Caulerpa sp. in Darwin´s reef; ii) map the coral area; iii) get ecological monitory data to know the actual conditions of the coral areas. This research was conducted in the new “marine sanctuary” confirmed by the small islands of Darwin and Wolf on the north side of the Archipelago. As a result of this expedition, they were able to determinate that Darwin and Wolf reef communities are in good conditions. Some samples and small colonies were observed. Important reef areas are being affected because of the overgrowth of the Caulerpa sp. seaweed. The territory has increased in recent years (at least, from 2015).

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Halmos Faculty Identify More than 180 Species of Fish

Halmos faculty member Tracey Sutton, Ph.D. and other scientists of the DEEPEND consortium have identified over 180 fish species new to the Gulf of Mexico and another 20-30 that are new to scientists. Most of these species come from the deep waters of the Gulf, where little research has been conducted. “People don’t fish it and it requires specialized gear. Research vessel time is fairly expensive,” Sutton said. After four years of sampling, Sutton’s group found over 1600 species of fish in the Gulf. This is at least a 10% increase from the last count. Included in this count are never before seen fish, several called dragon fishes. “They’re quite horrible looking,” Sutton said. “They are fish with big teeth and a lure hanging off their chin that has a light organ hanging on the end to lure prey.” The DEEPEND consortium is part of the Gulf of Mexico Research Initiative. This was created as a result of the 2010 BP Deepwater Horizon oil spill. As part of their settlement, the oil company was required to give $500 million to 20 independent researches to explore the Gulf’s deep waters.

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NSU Biophysicist Studies the “Autocorrect” Feature in your DNA

New research at NSU has revealed the information content associated with each letter of DNA. This work may improve our understanding of how the genetic code can resist the effects of mutations that may cause cancer or inherited diseases. The same genetic code is used by almost all living organisms to translate three-letter “words,” or codons, of DNA into amino acids, which are strung together to form proteins. Assistant Professor Louis Nemzer, Ph.D., a biophysicist at the Halmos College of Natural Sciences and Oceanography, used methods from the field of information theory to calculate the “Shannon entropy” of each letter of DNA, depending on the type of base (A, T, G, or C) and its position in the codon. Although many people have never heard of Claude Shannon, his pioneering work at Bell Labs on measuring the maximum amount of information contained in messages is still crucial today for digital communication technologies, including text messaging, WiFi, and mobile data transmission. So why did Shannon choose to call his measure of information “entropy,” a word more associated with the physics of an ideal gas? “There are very close connections between thermodynamics and information theory” said Dr. Nemzer, “entropy in physics really just measures how much information about a system you are missing.”

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NSU Researcher Secures Grant to Study Zika

Vladimir Beljanski, Ph.D., associate professor in the NSU Cell Therapy Institute recently received grant award from the Florida Department of Health, Biomedical Research Program for a project titled, “A comparative analysis of Zika virus-induced antiviral response mechanisms in under-studied cell populations.” Findings produced from this project can help to develop new treatments for Zika virus and improve understanding of how this virus contributes to other medical conditions. The ongoing Zika virus disease epidemic is one of the largest epidemics ever recorded. Development of methods to reduce Zika infections and decrease longevity of infection could significantly reduce the number of infected individuals and alter clinical recommendations. While most of research focused on studying Zika’s harmful effects on brain development in newborns, the study proposes to examine other potential Zika infection-related health issues with dramatic clinical manifestations. For example, ocular defects have been observed in infants exposed to the virus. In adults, several neurological complications including Guillian-Barre Syndrome, meningoencephalitis, acute myelitis, and sensory polyneuropathy have also been associated with Zika infection. These conditions can be readily explained by the infection of many cell types throughout the body with Zika – cells that have received little to no attention from researchers. Therefore, it is possible that Zika infection may play more extensive roles in pathological conditions affecting adults, including autoimmune disorders, cardiovascular disease, cancer, and neurodegenerative diseases. A deeper understanding of the scope of Zika infection in both developing babies and adults will help guide policy makers as they develop guidelines and direct public health efforts. Because the antiviral mechanisms that clear Zika infection differ between cells and their developmental stages, the study proposes to stimulate antiviral pathways with drugs using a collection of critical cell types, including glial, neuronal, vascular, retinal, and immune cell types to examine both cell function in the presence of Zika infection and to examine antiviral response in such cells. This is a translational study that builds upon the mechanistic knowledge of antiviral signaling and cell differentiation and applies it to the evaluation of potent antiviral strategies with a goal to decrease severe deleterious health effects of Zika infection. This pilot proposal will provide novel information with regards to clinical targeting of antiviral mechanisms and will determine potential side effects of such targeting. This information may benefit all individuals diagnosed with Zika infection. The research team consists of Vladimir Beljanski, Ph.D. (principal investigator), and Adil Duru, Ph.D., assistant professors at NSU Cell Therapy Institute, Benjamin Josey, Ph.D., a post-doctoral researcher in the institute, Outi Hovatta, Ph.D., a NSU visiting scientist from Karolinska Institutet, and Lubov Nathanson, Ph.D., from the NSU Institute for Neuro-Immune Medicine.

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Nova Southeastern University Scientists Study Disease that Impacts Hundreds of Thousands of Gulf War Veterans

As the nation honors our veterans on November 11, we must pause to remember the long-lasting health effects soldiers experience not only from bullets or bombs, but from exposure to unexplained pesticides, radiation or other toxins during their time in the service. At least a quarter of the 700,000 soldiers who fought in the 1991 Gulf War suffer from a debilitating disease called Gulf War illness (GWI).

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Private Concert Benefits Nova Southeastern University’s Sarcoma Research Fund

An intimate group of philanthropists, health care and community leaders and music lovers recently gathered at the NSU Art Museum Fort Lauderdale for a private performance by renowned pianist Kemal Gekic. The fundraiser was held in collaboration with The International Piano Festival in Miami and the American Cancer Society to benefit Nova Southeastern University’s (NSU) Sarcoma Research Fund, part of Realizing Potential – The Campaign for Nova Southeastern University.

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New “Ugly” Deep-Sea Angler Fish Named One of Top 10 Discoveries of the Past Year

FOR IMMEDIATE RELEASE FORT LAUDERDALE/DAVIE, Fla. – It’s the little fish that keeps on giving. During a research trip in the Gulf of Mexico, Tracey Sutton, Ph.D., an associate professor at Nova Southeastern University’s (NSU) Halmos College of Natural Sciences and Oceanography, made quite the discovery. Dr. Sutton, who…

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Updated: HCA East Florida Receives State Approval for a New Hospital to be Built on the Campus of Nova Southeastern University

FOR IMMEDIATE RELEASE Updated May 18, 2016: Florida’s Agency for Health Care Administration submitted its final approval for HCA East Florida to relocate Plantation General Hospital to Nova Southeastern University (NSU) in Davie on May 17, 2016. “This will propel us toward achieving NSU’s Vision 2020, providing the highest quality health…

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Researcher Spotlight: NSU Professor Receives World Class Faculty Award for Global Contributions to Science and Medicine

NSU researcher and faculty member Nancy Klimas, M.D., was recently named the World Class Faculty Award recipient by the Greater Fort Lauderdale Alliance at its 2016 Mid-Year Luncheon at the Hyatt Regency Pier 66 in Fort Lauderdale. “It is an honor to highlight Dr. Klimas as the Alliance’s 2016 World Class…

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NSU Research Spotlight: Evren Alici, M.D., Ph.D.

Evren Alici, M.D., Ph.D., director of the Gene and Cell Therapy Center at Karolinka Institutet in Sweden and a visiting research professor at the NSU Cell Therapy Institute, which will soon be housed in the Center for Collaborative Research. His research is focused on developing treatments for blood and bone…

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